Division of Reproductive Sciences

Our Mission

Our mission is to make discoveries and engage in research that promotes training of scientists and clinicians in research that fosters the development future research scientists and clinicians to become the future leaders in OB/GYN and reproductive research. The study of reproduction and embryonic development has recently flourished with the use of genetic mouse models. Building on these studies, our philosophy has been to use molecular, cellular, and computational methodologies coupled with genetic mouse models to identify key pathways in embryonic development, reproduction and gynecological malignancies.

Our expertise includes the study of angiogenesis, the construction of blood and lymphatic vessels. Using mice, we have identified pathways critical for angiogenesis, fibrosis, inflammation, and tumor growth. These models are advancing our knowledge of fertility, pregnancy, delivery and vascular disorders. Our research is conducted in newly developed laboratories situated in the OB/GYN department of the Herbert Irving Comprehensive Cancer Research Center.

Overview

The Division of Reproductive Sciences is organized to Discover, Research and engage in Scholarly activities to increase our understanding of reproduction, and to treat reproductive disorders and gynecological cancers.

  • We seek to Discover new mechanisms regulating reproduction and relate those discoveries to pathological situations important to women’s health, fertility, and successful pregnancy.
  • The Research we conduct uses the mouse as a model to follow successful fertilization, embryonic development, tissue function, and oncogenesis. We model gynecological malignancies to understand the cancer-inducing pathways and the role of new blood vessel development, angiogenesis, in tumor development. Based upon this knowledge, we have developed therapeutic agents that interfere with tumor angiogenesis and thus thwart tumor growth.
  • Scholarly activities include training and education of basic scientists, physician scientists, fellows, and students in reproductive and cancer biology.