Clinical Trials

  • Tired of having to remember to take your birth control? If you are a woman between the ages of 18 and 35, are pre-menopausal, sexually active and do NOT wish to become pregnant, you are invited to see if you may qualify for a research study. The purpose of this research study is to test the effectiveness of an investigational contraceptive vaginal ring. If you qualify, you will receive investigational study medication, study-related medical exams, and laboratory services at no charge. You may also be reimbursed for time, travel, and other expenses.
  • Test the safety and effectiveness of the research study drug, pembrolizumab (MK-3475) in combination with chemotherapy, compared to chemotherapy plus placebo (a look-alike drug with no active ingredients) in women with persistent, recurrent, or metastatic cervical cancer. To test if adding pembrolizumab (MK-3475) to standard chemotherapy improves survival women with persistent, recurrent, or metastatic cervical cancer. Pembrolizumab (MK-3475), also called KEYTRUDA has been approved for use in certain types of cancers; however it may not be approved to treat your type of cancer.
  • The main purpose of this study is to: Learn about the safety of REGN4018 and to find out what dose of REGN4018 can be given alone or in combination with cemiplimab to research subjects with ovarian cancer without too many side effects. The study will also look at the levels of REGN4018 and/or cemiplimab in the body and measure how well your body can remove the study drug(s). This is called pharmacokinetics. The study will also look at any signs that REGN4018 alone or with cemiplimab can treat cancer.
  • SY-1365 is an investigational drug that stops the function of a protein known as CDK7. Previous workhas shown that CDK7 is necessary for some cancers to grow. Therefore, SY-1365 could be used to slow down the growth of cancer. This research study is being done to understand the highest tolerated dose of SY-1365, and to assess the safety of SY-1365 in patients with advanced solid tumors where standard therapies are no longer effective or do not exist. "Investigational" means that SY-1365 has not been approved by the United States Food and Drug Administration (FDA).
  • We are doing this study to find out if tisotumab vedotin treats ovarian cancer. We want to see if patients with your kind of ovarian cancer respond to the drug. We want to see how long it takes patients to respond to tisotumab vedotin and how long the response lasts. We also want to learn more about any side effects patients have when they get tisotumab vedotin.Tisotumab vedotin is a type of drug called an antibody drug conjugate or ADC. ADCs usually have 2 parts. Antibody: Antibodies are part of your immune system. Usually, they help protect you from getting sick.
  • The study drug (TSR-042) in this study is designed to stop cancer from growing by helping your immune system recognize and fight the cancer. The Study Drug is designed to help your immune system by attaching to a protein called PD-1 and stopping one of the signals that keeps your immune system from recognizing the cancer. This may help your immune system attack and destroy the cancer cells.
  • The purpose of this study is to see how well an investigational new drug and study device combination work to treat women with pre-cancerous cells of the vulva caused by human papillomavirus (HPV) and,thereby avoid surgery. To participate in this study you must have high grade squamous intraepithelial lesion (HSIL) of the vulva caused by HPV types 16 or 18.
  • When women have a cesarean delivery, there is an amount of bleeding. Occasionally (in less than 5 of every 100 births) there is severe bleeding that can place the mothers health at risk. When there is too much bleeding after a cesarean delivery, women are given medicines, blood transfusions, or possibly need another surgery. Tranexamic acid is routinely used to lessen the chance of hemorrhage. It works by making your blood clot sooner. It is not routinely used for cesarean sections. We are doing this study to see if this drug also works for women who are having a cesarean section.
  • The purpose of this study, which involves research, is being done to see how well an investigational new drug and study device combination will work to treat people with pre-cancerous cells on the cervix caused by human papillomavirus (HPV). The treatment combination is testing a drug, called VGX-3100, given by injection and used with the study device, CELLECTRA 5PSP, that delivers a small electric charge through 5 needles to increase the amount of the study drug taken up by muscle.
  • We are asking you to participate in this research study because you are a woman of child-bearing age or potential and interested in using an intrauterine device (IUD) for birth control for up to 5 years.