PREPP: Practical Resources for Effective Postpartum Parenting
PREPP is a dyadically-oriented protocol for the prevention of postpartum depression. It uses targeted psychotherapy and infant behavior interventions in an brief and accessible model in conjunction with routine perinatal medical visits.
To learn more, please check out our publications:
Werner, E.A., Gustafsson, H.C., Lee, S., Feng, T., Jiang, N., Desai, P., Monk, C. (2016). PREPP: postpartum depression prevention through the mother-infant dyad. Archives of Women’s Mental Health, 19(2), 229-242
Interested in Receiving PREPP Training?
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Welcome to the Perinatal Pathways Lab
We conduct research studies with pregnant people and their babies to improve their well–being and their future children’s lives.
For over 25 years, we have contributed to the scientific evidence showing that when pregnant people experience stress, anxiety, and depression, it affects them as well as their offspring in utero. There is a ‘third pathway’ for the familial inheritance of risk for psychiatric illness beyond shared genes and the quality of parental care: the impact of pregnant people’s distress on fetal and infant brain–behavior development. Our projects involve fetal assessment, newborn neuro-imaging, genetics, epigenetics, psychoneuroimmunology, mother–child interaction, and supportive interventions to (1) characterize maternal experiences and the effects on children’s development and (2) promote maternal psychobiological health for the mother–child dyad.
We are actively recruiting for several studies. In our research studies, we are generally interested in people’s experiences during pregnancy and how people can feel less stressed during pregnancy and postpartum. If you are interested in participating and/or learning more about our studies, please click here.
Learn More
- Learn more about PREPP and our training opportunities.
-Learn more about the COMBO project, a collaborative multi-lab effort focusing on the effects of COVID-19 on parents and babies.
-Learn about Drs. Monk and Werner’s mental health service, the Division of Women’s Mental Health @Ob/Gyn, embedded within the Department of Obstetrics and Gynecology at Columbia University Irving Medical Center / NewYork-Presbyterian.
Dr. Monk serves on the board of Marcé of North America (MONA), Zero To Three (ZTT) and the International Marcé Society. Learn more about their missions here:
Our Approach
We study a possible third pathway by which risk for psychiatric disorders runs in families.
We investigate pregnant women’s experiences — depression, stress, medication use, and nutrition — as they shape fetal and infant neurobehavioral development, with implications for the future child’s mental health. This research pushes the study of the mother–infant dyad to an earlier time, prior to birth, and considers psychological and biological factors as the mechanisms of maternal influence. We also conduct clinical trials of interventions during the perinatal period to improve women’s well-being for her, and for her child.
Our work is part of a burgeoning research domain known as the developmental origins of health and disease (DoHAD).
Based on animal models as well as epidemiological and observational samples, findings indicate that distress–based changes in pregnant women’s biology are associated with adverse cardiovascular, metabolic, as well as psychological effects in children and adults. In our DoHAD studies, we focus on the perinatal period, the time when the maternal influence is thought to occur, and on children’s neurobehavioral development. We have four primary research questions carried out across a number of studies.
We Aim To
detect variation in fetal development associated with maternal distress, poor nutrition, and/or use of psychiatric medication and determine the relevance of these fetal characteristics to children’s future functioning
use MRI and EEG methodology to characterize differences in newborn brain development related to these prenatal exposures, and to determine the functional significance of these differences in terms of infant behavior and as they may be modified by postnatal factors such as maternal caregiving sensitivity
identify biological processes for the transmission of pregnant women’s experience to the fetus based on the following methodology: ambulatory assessment of blood pressure, HPA axis, immune activity; methylation in cord blood and placenta; mood and nutrition reports
determine if successful psychotherapeutic intervention with depressed and/or highly stressed pregnant women can improve women’s functioning and the neurobehavioral profile of the offspring, suggesting less risk of mental health disorders in the future.
Our Approach
psychology and biology as different levels of analysis having bi–directional influences;
development as a construction that reflects a succession of adaptations that evolve over time with change constrained by prior adaptation yet possible at many points (Sroufe, 1997).
Current Studies
Stress phenotypes and preterm birth: immune and energetic cellular dysregulation and the preventive effect of social support
(1 R01MD016278-01; Monk, C., Gyamfi-Bannerman, C., Picard, M., Trumpff, C. (MPI))
At odds with common assumptions — and hope, pregnancy ends in preterm birth (PTB) for approximately 1 in 10 women. Yearly PTB affects 15 million infants worldwide and 386,580 in the United States. PTB is the leading cause of global, and U.S., neonatal mortality and morbidity and is associated with future risk for poor physical (higher blood pressure, chronic kidney disease, wheeze/asthma) and mental (ADHD, IQ decrements) health. Maternal health is not spared: women who deliver preterm are at an increased risk for depression, hypertension, cardiovascular and renal disease later in life. In the U.S., the racial and ethnic disparities in PTB rates are dramatic and independent of socio-economic status (SES): overall, 14.12% for Non-Hispanic Black compared to 9.09% for Non-Hispanic White women.
Psychosocial stress and childhood trauma each are associated with risk for PTB. PTB has an intergenerational impact: mothers born preterm are more likely to give birth pretern, especially amongst Black women. Biomarkers to predict PTB have proven unsuccessful, and do not account for this emerging recognition of intergenerational transmission of PTB risk specifically via maternal heritage. Mitochondria, which contain their own genome, the mitochondria DNA, are inherited from the mother and represent a potential intersection point between psychosocial experiences and their biological embedding, including via immune dysregulation, in underlying disease outcomes. We aim to apply a mitochondria psychobiology approach to delineate by which mechanisms life stress — including discrimination and childhood trauma — results in disproportionate risk of PTB in minority women, and evaluate mitochondria as potential biomarkers of this birth outcome.
In a sample of post-attrition n=175 pregnant women we will test the following three aims: Aim 1: To determine whether a data driven approach to multiple, 1st trimester psychosocial (self- report stress discrimination, 24-hour ambulatory mood, social support), lifecourse (hair cortisol, childhood trauma), and biological variables (acute laboratory physiological stress reactivity) generate unique stress profiles that partially explain the racial/ethnic differences in gestational age at birth. Aim 2: To identify molecular indices of mitochondrial and immune functioning in the mother (3x blood draw), placenta, and fetal cord blood that mediate the association between 1st trimester maternal stress phenotypes and risk for earlier gestational age at birth. Aim 3: To evaluate if reduction in stress levels and/or improvement in social support over the course of pregnancy is associated with molecular indices of mitochondrial and immune functioning and (exploratory) reduced risk of earlier birth relative to national and hospital norms.
This new conceptual framing of this adverse health outcome (1) incorporates evidence of the psychosocial factors contributing to risk, (2) aims to account for the racial/ethnic disparities, and (3) harnesses cutting-edge mitochondria knowledge and tools to better characterize PTB’s pathophysiology and identify novel targets for its intervention and prevention.
COVID-19 mother baby outcomes (COMBO): brain-behavior functioning
(1 R01MH126531-01; Dumitriu, D., Marsh, R., Monk, C. (MPI))
The devastating effects of the COVID-19 pandemic have reverberated through every aspect of our civilization. While SARS-CoV-2, the viral etiology of COVID-19, seems to spare infants in terms of actual infection, it is currently unknown whether maternal infection during pregnancy will have long-term effects on children born during the pandemic. A variety of prenatal insults, including infections and stress, are well-known to lead to increased risk of affective disorders in both mother and child. With its disproportionate reach into already disadvantaged minority communities, the impact of the COVID-19 pandemic on the dyad is currently unknown and potentially of unprecedented magnitude with enduring consequences for women's mental health and children's developmental origins of health and disease (DOHaD).
The COVID-19 Mother Baby Outcome (COMBO) initiative, a large multidisciplinary collaborative, was established at Columbia University Irving Medical Center to follow SARS-CoV-2 exposed laboring mothers and their newborns and compare their long- term health outcomes to case-matched dyads without prenatal exposure. This proposal will follow a subset of the larger COMBO cohort to study socioemotional circuits (fronto-limbic) and behavior (caregiving and bonding) in 100 mother-child dyads from prepartum to 18 months postpartum.
The team assembled to carry out this study consists of two provider scientists (Dumitriu, pediatrician and neuroscientist, & Monk, clinical psychologist embedded in Ob/Gyn) and neuroscientist/pediatric neuroimager (Marsh). Using an innovative dyadic approach, olfaction testing, multimodal MRI, wearable in-home physiological recordings, observational mother and child assessments (free play, routine care, Harvard Reactivity and Still Face paradigms), this proposal will test the overarching hypothesis that prenatal SARS-CoV-2 exposure affects (1) mother and (2) child brain and behavior, and (3) demonstrate that the socioemotional health of each member of the mother- child dyad is intrinsically related to that of the other. Detecting COVID-19-related early neurobehavioral effects on mothers and the next generation will provide insights into intervention strategies and contribute significantly to DOHaD and stress science.
Intergenerational transmission of deficits in self-regulatory control
(1 R01 1R01MH117983; Spann, M., Marsh, R., Monk, C. (MPI))
Self-regulatory deficits are common across a variety of childhood psychiatric disorders in which children have difficulty regulating their thoughts, emotions, and behaviors. By leveraging previously collected prenatal and neonatal data and acquiring new data from mother-infant dyads, this study will identify circuit-based markers of regulatory deficits that are passed inter-generationally, and persist from infancy to childhood.
We will enroll 15- 45 year-old pregnant women/mothers, approximately 75% Latina, who are receiving health care from our urban medical center, a sample that is underrepresented in U.S. biomedical research and facing significant psychosocial adversity. Age-appropriate measures of regulatory control processes will be acquired from their off- spring at 4- and 14-months and during preschool and school age, including resting-state fMRI data from neo- nates and both resting and task-based fMRI data from school-aged children who were previously scanned as neonates. Behavioral measures of regulatory capacity and resting and task-based fMRI will also be acquired from the mothers, allowing us to associate maternal-neonatal indices of self-regulatory control.
Thus, this study will uncover trajectories of control processes and circuits from infancy to school age and the intergenerational transmission of regulatory deficits from mothers to offspring. Findings will set the stage for future research aimed at engaging these circuits as targets for strategies to prevent the risk for future maladaptive behaviors and at identifying prenatal mechanisms underlying the intergenerational transmission of regulatory deficits, such as epigenetic and stress-mediated biological alterations.
This study supports the NIMH strategic objective to chart mental illness trajectories to determine when, where, and how to intervene by elucidating the development of regulatory control across the first decade of life. This study also supports both the NIH BRAIN and precision medicine initiatives by evaluating the functional organization of control circuits across family generations and longitudinally, as well as using a novel imaging method to predict behavioral outcomes.
Preventing postpartum depression: A dyadic approach adjunctive to obstetric care
(1 R01 HD092062-01; Monk, PI)
Of the nearly 4 million live births each year in the United States, approximately 560,000, or 14% of these women will develop depression within the first four months postpartum. The consequences are substantial: diminished quality of life and significant emotional suffering for women. PPD predicts diminished mother–infant bonding and poor outcomes in social–emotional and, for some, cognitive development.
Relying on standard pharmacologic and psychological interventions, PPD is undertreated in part because women are reluctant to seek treatment due to the stigma associated with mental health care, logistical barriers to attending added health care appointments, and disinclination to take medications while breastfeeding. Risk factors for PPD are relatively well delineated. Even though prenatal depressive symptoms are some of the most reliable predictors, evidenced–based, preventive interventions for PPD are rare. Of the preventative interventions, few leverage the unique dyadic orientation of the childbearing period or imbed services in obstetrical care.
To address the huge knowledge gap in the prevention and treatment of PPD, we developed (R21MH092665–01) and tested in a preliminary randomized control trial (RCT) a new intervention called PREPP (Practical Resources for Effective Postpartum Parenting) and, following promising published data, we propose to conduct a larger RCT of this treatment.
PREPP enrolls pregnant women at risk for PPD, spans late pregnancy to the 6– week postpartum check up. It consists of four in–person ‘coaching’ sessions adjunctive to obstetrical (OB) prenatal and postnatal appointments, and one phone session. PREPP includes (a) mindfulness and self– reflection skills, (b) parenting skills and (c) psycho–education. For this proposed project, we have three study aims to be realized in a PREPP vs Enhanced Treatment as Usual RCT of 214, 3rd trimester pregnant women (ages 18–35) at risk for PPD assessed 2x in pregnancy and at 6, 12, and 16 weeks postpartum: (1) Reduce women’s distress during pregnancy (2) Determine the maintenance of improved maternal mood and differences in infant behavior (3) Identify some of the pathways by which PREPP positively affects the mother– infant dyad.
PREPP is innovative in its novel conceptualization of PPD and design to overcome barriers to PPD treatment. The traditional clinical approach to PPD has as a focus the individual and improving their symptoms. In PREPP, PPD is viewed as a potential disorder of the mother–infant dyad, which can be approached through preventive psychological and behavioral changes in the mother — commencing before birth — that affect her and the child.
PREPP exemplifies the vanguard of health care innovations aiming to increase metal health care uptake by integrating behavioral health services with primary health care. The proposed research is significant because it is expected to advance the treatment and prevention of PPD, and generate new knowledge about mother–infant behavioral influences during the first months of postnatal life.
Breaking the cycle of intergenerational disadvantage: neurodevelopment among Puerto Rican children
(1UG3OD023328-01; Duarte, C., Canino, G.J., Monk, C., Posner, J.(MPI))
Disadvantage can ensnare families for generations. Existing studies have identified the effects of childhood adversity on neurodevelopment in decrements in cognitive and social outcomes. This timeframe, however, may be too constricted, assiduously focusing on intra-generational effects, while ignoring inter-generational determinants. Considering a child’s own adverse exposures, without noting experiences of adversity in that child’s parents, may obscure intergenerational effects.
Within an established, well-characterized, inter- generational and disadvantaged cohort, we aim to determine key factors influencing the cycle of disadvantage in which so many families get caught for generations. Our outcome of focus is neurodevelopment as indexed by executive functions (EF) and MRI measures of related neural substrates. EF dysfunctions are key determinants of subsequent social and occupational challenges. We also examine protective factors that may contribute to breaking this cycle of disadvantage and yield favorable neurodevelopmental outcomes.
We would bring to the ECHO consortium a multi-generation, population–based sample of 2,491 Puerto Ricans living in the South Bronx, NY and San Juan, PR. The first generation of the cohort (G1) was assessed prospectively at 3 times points in childhood/early adolescence (ages 5-13) and once in late adolescence/early adulthood (ongoing). When ECHO is launched, G1 will be in early adulthood, and just beginning to have their own children (Generation 2 or G2 Probands). Our cohort is thus optimally poised to examine the effects of adversity during early childhood using a prospective design. We will assess G2 Probands including all new births during the study period (Prenatal/Birth Cohort, n~650) and all G2 Proband children born prior to the start of ECHO (Child Cohort, ages 3-10, n~830).
We will use neuroimaging and behavioral assessments to characterize the influence of many forms of adverse exposures (e.g., physical abuse, neglect, parental mental illness). We will examine how one generation’s experience of adversities may affect the development of the next, and how different sources of exposure, those experienced by one’s parents as well as those a child faces on his or her own, impact neurodevelopmental outcomes. Our multidisciplinary team brings expertise in the epidemiology of disadvantaged populations (MPIs Duarte & Canino), fetal origins of health and disease (MPI Monk), and developmental neuroscience (MPI Posner).
In addition to our specific aims, our study will enrich the ECHO consortium by providing biospecimens including DNA, placenta, cord blood, and deciduous teeth. These specimens will allow the ECHO consortium to investigate the influence of genetic and epigenetic factors as well as chemical exposures during early development within a high-risk, but understudied, population. In sum, our investigative team, the uniqueness of our cohort, and the novelty of our focus on intergenerational influences offer distinct contributions to the ECHO project both in terms of the specific aims of our proposal and to the larger goals of the ECHO consortium.
Our Team
Catherine Monk
Publications
Research Gate
Curriculum Vitae
Catherine Monk, PhD, is the inaugural Diana Vagelos Professor of Women’s Mental Health in the Department of Obstetrics & Gynecology and Professor of Medical Psychology in the Department of Psychiatry at Columbia University Vagelos College of Physicians and Surgeons and Research Scientist VI at the New York State Psychiatric Institute. Dr. Monk oversees the clinical service, the Division of Women’s Mental Health @Ob/Gyn, an embedded mental health program in the Department of Obstetrics & Gynecology at Columbia University Irving Medical Center / NewYork-Presbyterian.
Dr. Monk’s research brings together the fields of psychopathology, developmental psychobiology, developmental neuroscience, and perinatal psychiatry to focus on the earliest influences on children’s developmental trajectories—those that happen in utero—and how to intervene early to prevent mental health problems. She collaborates with colleagues to include biological and psychological processes in her research, e.g., using MRI techniques to study variation in brain development related to prenatal maternal factors such as distress and poor nutrition, examining gene expression in placentas related to similar maternal variables. Her research has been continuously funded by NIH since her NIMH Career Development award in 2000.
Elizabeth Werner
Elizabeth Werner, PhD, is an Assistant Professor of Behavioral Medicine in the Departments of Obstetrics & Gynecology and Psychiatry, Columbia University Irving Medical Center and serves as the Senior Director of Research Operations and the Director of Clinical Intervention Research in the Perinatal Pathways Lab. Dr. Werner is the Lead Supervising Clinician in the PREPP program, a clinical research trial aimed at preventing Postpartum Depression. She also is the Associate Director of Women’s Mental Health @Ob/Gyn, through which she also provides clinical care. Dr. Werner specializes in the treatment of mood disorders and stress management, particularly working with women during the perinatal period, during struggles with fertility and during assisted reproduction interventions.
Dr. Werner is a Co-Investigator on several projects funded by the NIH, and has published papers on a variety of topics in the fields of perinatal psychiatry and developmental psychobiology. She was selected as a NIH CHIPS fellow (Child Intervention, Prevention, and Services) and as a New York State Office of Mental Health Policy Scholar.
Marisa Spann
Marisa Spann, PhD, MPH, is an Assistant Professor of Medical Psychology in the Department of Psychiatry. Dr. Spann is a clinical neuropsychologist with specialty training in developmental neuroimaging and perinatal epidemiology. She obtained her PhD in clinical psychology at George Washington University. She went on to pursue a clinical neuropsychology postdoctoral fellowship at Yale University School of Medicine in the Department of Neurosurgery. During this time she obtained her masters of public health at Yale School of Public Health. She transitioned to a NIH-funded T32 research postdoctoral fellowship in Translational Child Psychiatry at Columbia University Medical Center (CUMC). Since diagnostic mental health symptoms are not obvious before preschool to school age, the overarching goal of Dr. Spann’s research is to identify prenatal and infant biomarkers of emerging mental health risk. Her research focuses on how prenatal immune-activating exposures, such as maternal infection, medical conditions, and environmental stressors affect fetal and infant brain (structure and connectivity) and mental health (attention and behavioral reactivity) development. She is involved in ongoing epidemiologic studies utilizing international birth cohorts and clinical studies at CUMC that investigate the role of maternal immune activation during pregnancy as measured by maternal blood/sera on development from the fetal period to childhood. Isolating developmental markers that cut across child psychiatric disorders during this early period of development will help ensure identification of a greater number of children at risk. Her research has been funded through the Gray Matters (Department of Psychiatry at CUMC), Whitaker Developmental Neuropsychiatry Scholar (Marilyn and James Simons Family Giving), TRANSFORM KL2 Mentored Career Development (Irving Institute for Clinical and Translational Research at CUMC and NIH), and Arts & Neuroscience Fellowship (Italian Academy for Advanced Studies in the America at Columbia University) awards.
Vanessa Babineau
Vanessa Babineau, PhD, is an Assistant Professor of Medical Psychology in the Departments of Obstetrics & Gynecology and Psychiatry at Columbia University Vagelos College of Physicians and Surgeons. She is the recipient of a K99/R00 Pathway to Independence Award from NIH. Her research interests are to identify behavioral pathways through which mental health disorders are transmitted across generations, with a focus on oppressed populations at greater risk for intergenerational trauma transmission based on social determinants of health (SDoH). She studies women’s mental health during pregnancy, such as depression, anxiety, and bipolar disorder, within the context of transition to parenthood among women who have a history of childhood maltreatment. Mother-child dyads are followed longitudinally to identify associations with fetal and newborn brain development, early childhood regulation, attachment, child brain-behavior development, and risk for psychopathology. She is also a clinician and researcher in PREPP (Practical Resources for Effective Postpartum Parenting), a clinical research trial aimed at preventing postpartum depression.
Dr. Babineau completed a Master of Arts and PhD in Child Psychology at McGill University, and a Postdoctoral Research Fellowship in Obstetrics & Gynecology at Columbia University. She received a Canadian Institutes of Health Research (CIHR) Doctoral Vanier Scholarship and CIHR Postdoctoral Fellowship. She completed clinical internships at the Jewish General Hospital in Montreal and at the William Alanson White Institute in New York City.
Pamela Scorza
Pamela Scorza is Associate Research Scientist in the department of Obstetrics and Gynecology at Columbia University. Dr. Scorza studies intergenerational processes in the transmission of risk for poor mental health, with a focus on developing prevention intervention to break cycles of poor mental health in populations exposed to adversities. Dr. Scorza has conducted Global Mental Health implementation research in Rwanda, Burundi, and Peru during doctoral studies at the Harvard TH Chan School of Public health and post-doctoral studies at Columbia University. Dr. Scorza has expertise in cross-cultural psychiatric epidemiology, global mental health implementation science, and perinatal psychobiology. Her current translational research program focuses on epigenetics and maternal caregiving in longitudinal studies in Puerto Rico, the US, and the UK to identify targets of preventive interventions for mental health.
Grace Liu
Grace Liu, MA, is the Data Manager in the Division of Behavioral Medicine in Psychiatry at Columbia University Medical Center. Grace provides comprehensive data services for the Division including data collection design, data quality checking, data reporting and data customization utilizing SAS, Excel/VBA, and other analytical packages. She also maintains and updates REDCap software and software/database installation supporting all users from the Division. Grace Liu holds a M.A. in Geographical Informational Systems and previously worked as an analyst in the nonprofit sector.
Graduate Students
Madalyn Osbourne
Madalyn Osbourne, B.A., is a doctoral student in Clinical Psychology at Long Island University, Brooklyn. She has been in the Perinatal Pathways lab since 2021, where she started by coordinating the Preterm Birth (PTB) R01 study, which examines the relationship between mood, stress, and inflammation, and the racial disparities in birth outcomes. Her graduate research is focused on complex and intergenerational trauma, attachment, and socioeconomic disadvantage and inequality.
Clinical Research Manager
Khadija Jones
Khadija Jones, MPH, is a doctoral student at the CUNY Graduate School of Public Health and Health Policy, currently holding the position of Clinical Research Manager within the Perinatal Pathways Lab. With a robust background in global health research, Khadija excels in designing, implementing, & evaluating programs aimed at aiding health systems and their diverse patient populations manage multiple chronic conditions on a global scale. Additionally, she possesses proficiency in conducting mixed methods maternal & child health research, with a focus on urban settings.
Khadija's interests lie in breaking down barriers to accessing care, addressing health disparities, and advocating for health equity. She is particularly passionate about women's health across the care continuum, delving into areas such as women's mental health and exploring the intricate relationship between intergenerational trauma, cultural influences, and socioeconomic disparities. Her commitment extends to leveraging research as a catalyst for health equity and utilizing mixed methods research to shape evidence-based, person-centered interventions & sustainable solutions.
Khadija earned her Bachelor of Science in Cell and Molecular Biology with a minor in Sociology from Binghamton University and furthered her academic journey with a Master in Public Health from Hofstra University.
Lab Manager
Stanley Ruiz
Yamille Stanley Ruiz, B.S., graduated from Cornell University in 2016 with a degree in Human Biology and a concentration in Human Development. He joined Perinatal Pathways in 2022 as Lab Manager and the Women’s Mental Health @Ob/Gyn team as Program Coordinator. He is also currently lead research coordinator for the Stress Phenotypes and Preterm Birth (PTB) R01 study, which examines the relationship between mood, stress, and inflammation, and racial disparities in birth outcomes. His interests include expanding access for mental health services for perinatal patients and using precision medicine initiatives as approaches for improving perinatal outcomes for mothers and infants, especially in underrepresented populations in research & underserved populations in healthcare. Beginning in summer 2024, he will pursue a master’s program in Physician Assistant studies.
Research Coordinators
Myrriam Grubb
Myrriam Grubb, B.A., graduated from Columbia University in 2022 with a degree in Psychology. She currently coordinates the Practical Resources for Effective Postpartum Parenting (PREPP) R01 study, which examines a behavioral intervention targeting maternal caregiving by combining mindfulness skills, psychoeducation, and parenting techniques for pregnant women at risk for postpartum depression. She is interested in integrative behavioral health/primary care models and working with minority and immigrant populations. In the future, Myrriam plans to pursue an MD, specializing in women’s health.
Caroline Tucker
Caroline Tucker, B.A., is currently completing her M.A. in Clinical Psychology and an Advanced Certification in Sexuality, Women, and Gender with a focus in Reproductive and Maternal Well-being at Teacher's College, Columbia University. She is currently a clinical research aide on the COVID-19 mother baby outcomes (COMBO) study at Perinatal Pathways. Caroline's research interests include the treatment of neurodevelopmental disorders in pregnancy and the effect of PMADs within partnered relationships.
Our Publications
2024
Pollatou, A., Holland, C. M., Stockton, T. J., Peterson, B. S., Scheinost, D., Monk, C., & Spann, M. N. (2024). Mapping early brain-body interactions: associations of fetal heart rate variation with newborn brainstem, hypothalamic, and dorsal anterior cingulate cortex functional connectivity. The Journal of neuroscience : the official journal of the Society for Neuroscience, e2363232024. https://doi.org/10.1523/JNEUROSCI.2363-23.2024. [Early release, advance online publication]
Aris, I. M., Lin, P. D., Wu, A. J., Dabelea, D., Lester, B. M., Wright, R. J., Karagas, M. R., Kerver, J. M., Dunlop, A. L., Joseph, C. L. M., Camargo, C. A., Jr, Ganiban, J. M., Schmidt, R. J., Strakovsky, R. S., McEvoy, C. T., Hipwell, A. E., O'Shea, T. M., McCormack, L. A., Maldonado, L. E., Niu, Z., Ferrara, A., Zhu, Y., Chehab, R.F., Kinsey, E.W., Bush, N.R., Nguyen, R.H.N., Carroll, K.N., Barrett, E.S., Lyall, K., Sims-Taylor, L.M., Trasande, L., Biagini, J.M., Breton, C.V., Patti, M.A., Coull, B., Amutah-Onukagha, N., Hacker, M.R., Jamestodd, T., Oken, E., on behalf of program collaborators for Environmental influences on Child Health Outcomes, on behalf of ECHO Components, ECHO Components, S. PB, N. LK, J. LP, C. DJ, F. G, G. R, C. D, ECHO Awardees and Cohorts (2024). Birth Outcomes in Relation to Neighborhood Food Access and Individual Food Insecurity During Pregnancy in the Environmental influences on Child Health Outcomes (ECHO)-Wide Cohort Study. The American journal of clinical nutrition, S0002-9165(24)00168-0. Advance online publication. https://doi.org/10.1016/j.ajcnut.2024.02.022. [In Press, Journal Pre-proof]
Lugo-Candelas, C., & Monk, C. (2024). System-level approaches to perinatal depression. The Lancet, 9(1), e4–e5. https://doi.org/10.1016/S2468-2667(23)00304-3
Spann, M. N., Alleyne, K., Holland, C. M., Davids, A., Pierre-Louis, A., Bang, C., Oyeneye, V., Kiflom, R., Shea, E., Cheng, B., Peterson, B. S., Monk, C., & Scheinost, D. (2024). The effects of experience of discrimination and acculturation during pregnancy on the developing offspring brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 49(2), 476–485. https://doi.org/10.1038/s41386-023-01765-3
2023
Monk, C. (2023). Editorial: In Utero Exposure to Maternal Affective Symptoms: Prenatal Programming of Child Psychopathology is Independent of Shared Genes of Risk. Journal of the American Academy of Child and Adolescent Psychiatry, S0890-8567(23)02269-4. Advance online publication. https://doi.org/10.1016/j.jaac.2023.12.007
Barcelona, V., Abuaish, S., Lee, S., Harkins, S., Butler, A., Tycko, B., Baccarelli, A. A., Walsh, K., & Monk, C. E. (2023). Stress and DNA Methylation of Blood Leukocytes among Pregnant Latina Women. Epigenomes, 7(4), 27. https://doi.org/10.3390/epigenomes7040027
VanBronkhorst, S. B., Abraham, E., Dambreville, R., Ramos-Olazagasti, M. A., Wall, M., Saunders, D. C., Monk, C., Alegría, M., Canino, G. J., Bird, H., & Duarte, C. S. (2023). Sociocultural Risk and Resilience in the Context of Adverse Childhood Experiences. JAMA Psychiatry, e234900. Advance online publication. https://doi.org/10.1001/jamapsychiatry.2023.4900
Lugo‐Candelas, C., Tse Hwei, Lee, S., Lucchini, M., Alice Smaniotto Aizza, Kahn, L. G., Buß, C., O’Connor, T. G., Akhgar Ghassabian, Padula, A., Aschner, J. L., Deoni, S., Margolis, A., Canino, G., Monk, C., Posner, J., & Duarte, C. S. (2023). Prenatal sleep health and risk of offspring ADHD symptomatology and associated phenotypes: a prospective analysis of timing and sex differences in the ECHO cohort. The Lancet Regional Health - Americas. https://doi.org/10.1016/j.lana.2023.100609
Helpman, L., Lassri, D., Zsido, R. G., Monk, C., & Dauvermann, M.R. (2023). Editorial: Pathways of risk, resilience, and recovery: impact of stress and trauma on women and girls. Frontiers in Psychiatry, 14. https://doi.org/10.3389/fpsyt.2023.1290535
Lugo‐Candelas, C., Chang, L., Dworkin, J. D., Aw, N., Fields, A., Reed, H., Spann, M., Gilchrist, M., Hinds, W., Marsh, R., Fifer, W. P., Weissman, M. M., Foerster, B., Marina Giorgi Manin, Silva, I., Peterson, B. S., Carolina, A., Gingrich, J. A., Monk, C., Duarte, C. S., Jackowski, A., & Posner, J. (2023). Maternal childhood maltreatment: associations to offspring brain volume and white matter connectivity. Journal of Developmental Origins of Health and Disease, 1–11. https://doi.org/10.1017/s2040174423000247
Jacobson, M. H., Hamra, G. B., Monk, C., Crum, R. M., Upadhyaya, S., Avalos, L. A., Bastain, T. M., Barrett, E. S., Bush, N. R., Dunlop, A. L., Ferrara, A., Firestein, M. R., Hipwell, A. E., Kannan, K., Lewis, J., Meeker, J. D., Ruden, D. M., Starling, A. P., Watkins, D. J., Zhao, Q., Trasande, L., & Environmental Influences on Child Health Outcomes Consortium. (2023). Prenatal Exposure to Nonpersistent Environmental Chemicals and Postpartum Depression. JAMA Psychiatry. https://doi.org/10.1001/jamapsychiatry.2023.3542
Berry, O. O., Kaufman, P., Weiss, M., Fitelson, E., & Monk, C. (2023). Co-location of specialized mental health services in an intimate partner violence advocacy organization. Medicine, Science, and the Law. https://doi.org/10.1177/00258024231195496
VanBronkhorst, S. B., McCormack, C., Scorza, P., Lee, S., Feng, T., Hane, A., Duarte, C. S., & Monk, C. (2023). Maternal childhood trauma and observed maternal care behaviors with 4-month-old infants. Psychological Trauma: Theory, Research, Practice, and Policy. https://doi.org/10.1037/tra0001554
Umemoto, A., Zhou, Z., Millon, E. M., Koshy, C. S., Taylor, S. M., Spann, M., Monk, C., Marsh, R., Rosellini, A. J., & Auerbach, R. P. (2023). Intergenerational transmission of cognitive control capacity among children at risk for depression. Biological Psychology, 182, 108652–108652. https://doi.org/10.1016/j.biopsycho.2023.108652
Scorza, P., Duarte, C. S., Lee, S., Wu, H., Posner, J., Baccarelli, A., & Monk, C. (2023). Stage 2 Registered Report: Epigenetic intergenerational transmission: Mothers’ adverse childhood experiences and DNA methylation. Journal of the American Academy of Child & Adolescent Psychiatry. https://doi.org/10.1016/j.jaac.2023.02.018
van den Heuvel, M. I., Monk, C., Hendrix, C. L., Hect, J., Lee, S., Feng, T., & Thomason, M. E. (2023). Intergenerational transmission of maternal childhood maltreatment prior to birth: Effects on human fetal amygdala functional connectivity. Journal of the American Academy of Child & Adolescent Psychiatry (ahead of print). https://doi.org/10.1016/j.jaac.2023.03.020
Shuffrey, L. C., Morales, S., Jacobson, M. H., Bosquet Enlow, M., Ghassabian, A., Margolis, A. E., Lucchini, M., Carroll, K. N., Crum, R. M., Dabelea, D., Deutsch, A., Fifer, W. P., Goldson, B., Hockett, C. W., Mason, W. A., Jacobson, L. T., O’Connor, T. G., Pini, N., Rayport, Y., Sania, A., Trasande, L., Wright, R. J., Lee, S., Monk, C., program collaborators for Environmental influences on Child Health Outcomes (2023). Association of gestational diabetes mellitus and perinatal maternal depression with early childhood behavioral problems: An Environmental influences on Child Health Outcomes (ECHO) study. Child Development. https://doi.org/10.1111/cdev.13938
Firestein, M. R., Shuffrey, L. C., Hu, Y., Kyle, M., Hussain, M., Bianco, C., Hott, V., Hyman, S. P., Kyler, M., Rodriguez, C., Tejeda Romero, M., Tzul Lopez, H., Alcántara, C., Amso, D., Austin, J., Bain, J. M., Barbosa, J., Battarbee, A. N., Bruno, A., Ettinger, S., Factor-Litvak, P., Gilboa, S., Goldman, S., Gyamfi-Bannerman, C., Maniatis, P., Marsh, R., Morrill, T., Mourad, M., Muhle, R., Newes-Adeyi, G., Noble, K. G., O’Reilly, K. C., Penn, A. A., Reichle, L., Sania, A., Semenova, V., Silver, W. G., Smotrich, G., Tita, A. T., Tottenham, N., Varner, M., Welch, M. G., Zork, N., Garey, D., Fifer, W. P., Stockwell, M. S., Monk, C., Dawood, F., Dumitriu, D. (2023). Assessment of neurodevelopment in infants with and without exposure to asymptomatic or mild maternal SARS-COV-2 infection during pregnancy. JAMA Network Open, 6(4). https://doi.org/10.1001/jamanetworkopen.2023.7396
McCormack, C., Abuaish, S., & Monk, C. (2023). Is there an inflammatory profile of perinatal depression? Current Psychiatry Reports. https://doi.org/10.1007/s11920-023-01414-y
Kaňková, Š., Takács, L., Hlaváčová, J., Calda, P., Monk, C., & Havlíček, J. (2023). Disgust sensitivity in early pregnancy as a response to high pathogen risk. Frontiers in Psychology, 14, 1–11. https://doi.org/10.3389/fpsyg.2023.1015927
Moog, N. K., Cummings, P. D., Jackson, K. L., Aschner, J. L., Barrett, E. S., Bastain, T. M., Blackwell, C. K., Bosquet Enlow, M., Breton, C. V., Bush, N. R., Deoni, S. C., Duarte, C. S., Ferrara, A., Grant, T. L., Hipwell, A. E., Jones, K., Leve, L. D., Lovinsky-Desir, S., Miller, R. K., Monk, C., Oken, E., Posner, J., Schmidt, R. J., Wright, R. J., Entringer, S., Simhan, H. N., Wadhwa, P. D., O’Connor, T. G., Musci, R. J., Buss, C., ECHO collaborators (2023). Intergenerational transmission of the effects of maternal exposure to childhood maltreatment in the USA: A retrospective cohort study. The Lancet Public Health, 8(3). https://doi.org/10.1016/s2468-2667(23)00025-7
Bianco, C., Sania, A., Kyle, M. H., Beebe, B., Barbosa, J., Bence, M., Coskun, L., Fields, A., Firestein, M. R., Goldman, S., Hane, A., Hott, V., Hussain, M., Hyman, S., Lucchini, M., Marsh, R., Mollicone, I., Myers, M., Ofray, D., Pini, N., Rodriguez, C., Shuffrey, L. C., Tottenham, N., Welch, M. G., Fifer, W., Monk, C., Dumitriu, D., Amso, D (2023). Pandemic beyond the virus: maternal COVID-related postnatal stress is associated with infant temperament. Pediatric research, 93(1), 253–259. https://doi.org/10.1038/s41390-022-02071-2
Hipwell, A. E., Tung, I., Sherlock, P., Tang, X., McKee, K., McGrath, M., Alshawabkeh, A., Bastain, T., Breton, C. V., Cowell, W., Dabelea, D., Duarte, C. S., Dunlop, A. L., Ferrera, A., Herbstman, J. B., Hockett, C. W., Karagas, M. R., Keenan, K., Krafty, R. T., Monk, C., … program collaborators for Environmental influences on Child Health Outcomes (2023). Impact of sedentary behavior and emotional support on prenatal psychological distress and birth outcomes during the COVID-19 pandemic. Psychological medicine, 1–14. Advance online publication. https://doi-org.ezproxy.cul.columbia.edu/10.1017/S0033291723000314
Sacchi, C., De Carli, P., Gregorini, C., Monk, C., & Simonelli, A. (2023). In the pandemic from the womb. Prenatal exposure, maternal psychological stress and mental health in association with infant negative affect at 6 months of life. Development and psychopathology, 1–11. Advance online publication. doi:10.1017/S0954579423000093
Albers, S. M., Wen, T., Monk, C., Logue, T. C., D'Alton, M. E., Booker, W. A., & Friedman, A. M. (2023). Postpartum Psychosis during Delivery Hospitalizations and Postpartum Readmissions, 2016-2019. American journal of obstetrics & gynecology MFM, 100905. Advance online publication. https://doi.org/10.1016/j.ajogmf.2023.100905
Lugo-Candelas, C., Talati, A., Glickman, C., Hernandez, M., Scorza, P., Monk, C., Kubo, A., Wei, C., Sourander, A., & Duarte, C. S. (2023). Maternal mental health and offspring brain development: An umbrella review of prenatal interventions. Biological psychiatry, S0006-3223(23)00054-9. Advance online publication. https://doi.org/10.1016/j.biopsych.2023.01.026
2022
Babineau, V., Fonge, Y. N., Miller, E. S., Grobman, W. A., Ferguson, P. L., Hunt, K. J., Vena, J. E., Newman, R. B., Guille, C., Tita, A. T. N., Chandler-Laney, P. C., Lee, S., Feng, T., Scorza, P., Takács, L., Wapner, R. J., Palomares, K. T., Skupski, D. W., Nageotte, M. P., Sciscione, A. C., Gilman, S., & Monk, C. (2022). Associations of maternal prenatal stress and depressive symptoms with childhood neurobehavioral outcomes in the Echo Cohort of the NICHD fetal growth studies: Fetal growth velocity as a potential mediator. Journal of the American Academy of Child & Adolescent Psychiatry, 61(9), 1155–1167. https://doi.org/10.1016/j.jaac.2022.03.021
Logue, T. C., Wen, T., Monk, C., Guglielminotti, J., Huang, Y., Wright, J. D., D’Alton, M. E., & Friedman, A. M. (2022). Trends in and complications associated with mental health condition diagnoses during delivery hospitalizations. American Journal of Obstetrics and Gynecology, 226(3). https://doi.org/10.1016/j.ajog.2021.09.021
Shuffrey, L.C., Lucchini, M., Morales, S. et al. Gestational diabetes mellitus, prenatal maternal depression, and risk for postpartum depression: an Environmental influences on Child Health Outcomes (ECHO) Study. (2022). BMC Pregnancy Childbirth 22, 758. https://doi.org/10.1186/s12884-022-05049-4
Foss, S., Gustafsson, H. C., Berry, O. O., Hipwell, A. E., Werner, E. A., Peterson, B. S., & Monk, C. (2022). Associations between childhood maltreatment, poor sleep, and prenatal distress in pregnant adolescents. Development and Psychopathology, 34(3), 764–773. https://doi.org/10.1017/s0954579420002163
Gustafsson, H., Hammond, J., Spicer, J., Kuzava, S., Werner, E., Spann, M., Marsh, R., Feng, T., Lee, S., & Monk, C. (2022). Third trimester fetuses demonstrate priming, a form of implicit memory, in utero. Children, 9(11), 1670. https://doi.org/10.3390/children9111670
Shuffrey, L. C., Firestein, M. R., Kyle, M. H., Fields, A., Alcántara, C., Amso, D., Austin, J., Bain, J.M., Barbosa, J., Bence, M., Bianco, C., Fernández, C.R., Goldman, S., Gyamfi-Bannerman, C., Host, V., Hu, Y., Hussain, M., Factor-Litvak, P., Lucchini, M., Mandel, A., Marsh, R., McBrian, D., Moored, M., Muhle, R., Noble, K., Penn, A.A., Rodriguez, C., Santa, A., Silver, W.G., Reilly, K.C., Stockwell, M., Tottenham, N., Welch, M.G., Zork, N., Fifer, W.P., Monk, C., & Dumitriu, D. (2022). Association of birth during the COVID-19 pandemic with neurodevelopmental status at 6 months in infants with and without in utero exposure to maternal SARS-CoV-2 infection. JAMA pediatrics, 176(6), e215563-e215563. https://doi.org/10.1001/jamapediatrics.2021.5563
Firestein, M.R., Dumitriu, D., Marsh, R., Monk, C. (2022). Maternal Mental Health and Infant Development During the COVID-19 Pandemic. JAMA Psychiatry. Epub ahead of print. https://doi.org/10.1001/jamapsychiatry.2022.2591
Lucchini, M., Ordway, M.R., Kyle, M.H., Pini, N., Barbosa, J.R., Sania, A., Shuffrey, L.C., Fernández, C.R., Fifer, W.P., Alcántara, C., Monk, C.E., Dumitriu, D. (2022). Racial/ethnic disparities in infant sleep in the COVID-19 Mother-Baby Outcomes (COMBO) study. Sleep Health. Epub ahead of print. https://doi.org/10.1016/j.sleh.2022.06.010
Hendrix, C.L., Werchan, D., Lenniger, C., Ablow, J.C., Amstadter, A.B., Austin, A., Babineau, V., Bogat, G.A., Cioffredi, L.A., Conradt, E., Crowell, S.E., Dumitriu, D., Elliott, A.J., Fifer, W., Firestein, M., Gao, W., Gotlib, I., Graham, A., Gregory, K.D., Gustafsson, H., Havens, K.L., Hockett, C., Howell, B.R., Humphreys, K.L., Jallo, N., King, L.S., Kinser, P.A., Levendosky, A.A., Lonstein, J.S., Lucchini, M., Marcus, R., Monk, C., Moyer, S., Muzik, M., Nuttall, A.K., Potter, A.S., Rogers, C., Salisbury, A., Shuffrey, L.C., Smith, B.A., Smyser, C.D., Smith, L., Sullivan, E., Zhou, J., Brito, N.H., Thomason, M.E. (2022). Geotemporal analysis of perinatal care changes and maternal mental health: an example from the COVID-19 pandemic. Archives of Women’s Mental Health. Epub ahead of print. https://doi.org/10.1007/s00737-022-01252-6
Rome, D., Sales, A., Leeds, R., Usseglio, J., Cornelius, T., Monk, C., Smolderen, K. G., & Moise, N. (2022). A Narrative Review of the Association Between Depression and Heart Disease Among Women: Prevalence, Mechanisms of Action, and Treatment. Current Atherosclerosis Reports, 10.1007/s11883-022-01048-0. Advance online publication. https://doi.org/10.1007/s11883-022-01048-0
Monk, C., Dimidjian, S., Galinsky, E., Gregory, K. D., Hoffman, M. C., Howell, E. A., Miller, E. S., Osborne, C., Rogers, C. E., Saxbe, D. E., & D'Alton, M. E. (2022). The transition to parenthood in obstetrics: enhancing prenatal care for 2-generation impact. American Journal of Obstetrics & Gynecology MFM, 4(5), 100678. Advance online publication. https://doi.org/10.1016/j.ajogmf.2022.100678
Scorza, P., Corbeil, T., Wall, M., Monk, C., Suglia, S., Wainberg, M., Alegria, M., Canino, G., Bird, H., & Duarte, C. S. (2022). Adverse childhood experiences and perceived stress in early adulthood in the context of disadvantage. Child Abuse & Neglect, 131, 105687. Advance online publication. https://doi.org/10.1016/j.chiabu.2022.105687
Wang, Y., Haghpanah, F. S., Zhang, X., Santamaria, K., da Costa Aguiar Alves, G. K., Bruno, E., Aw, N., Maddocks, A., Duarte, C. S., Monk, C., Laine, A., Posner, J., & program collaborators for Environmental influences on Child Health Outcomes (2022). ID-Seg: an infant deep learning-based segmentation framework to improve limbic structure estimates. Brain Informatics, 9(1), 12. https://doi.org/10.1186/s40708-022-00161-9
Kaňková, Š., Takács, L., Krulová, M., Hlaváčová, J., Nouzová, K., Hill, M., ... & Monk, C. (2022). Disgust sensitivity is negatively associated with immune system activity in early pregnancy: Direct support for the Compensatory Prophylaxis Hypothesis. Evolution and Human Behavior. https://doi.org/10.1016/j.evolhumbehav.2022.02.001
Monk C, Fernández CR. Neuroscience Advances and the Developmental Origins of Health and Disease Research. JAMA Network Open. 2022;5(4):e229251. doi:10.1001/jamanetworkopen.2022.9251
Babineau, V., McCormack, C. A., Feng, T., Lee, S., Berry, O., Knight, B. T., Newport, J. D., Stowe, Z. N., & Monk, C. (2022). Pregnant women with bipolar disorder who have a history of childhood maltreatment: Intergenerational effects of trauma on fetal neurodevelopment and birth outcomes. Bipolar Disorders, 10.1111/bdi.13207. Advance online publication. https://doi.org/10.1111/bdi.13207
Logue, T., Wen, T., Ogundimu, O., Monk, C., Guglielminotti, J., D’Alton, M., Friedman, A., (2022). Delivery hospitalizations with substance use disorder diagnoses. American Journal of Obstetrics and Gynecology. https://doi.org/10.1016/j.ajog.2022.02.039
Werchan, D. M., Hendrix, C. L., Ablow, J. C., Amstadter, A. B., Austin, A. C., Babineau, V., Anne Bogat, G., Cioffredi, L. A., Conradt, E., Crowell, S. E., Dumitriu, D., Fifer, W., Firestein, M. R., Gao, W., Gotlib, I. H., Graham, A. M., Gregory, K. D., Gustafsson, H. C., Havens, K. L., Howell, B. R., … Brito, N. H. (2022). Behavioral coping phenotypes and associated psychosocial outcomes of pregnant and postpartum women during the COVID-19 pandemic. Scientific Reports, 12(1), 1209. https://doi.org/10.1038/s41598-022-05299-4
Takács, L., Smolík, F., Lacinová, L., Daňsová, P., Feng, T., Mudrák, J., Zábrodská, K., & Monk, C. (2022). Emergency cesarean section is a risk factor for depressive symptoms when breastfeeding is limited. Journal of Psychosomatic Research (153), 110691.
Lucchini, M., Kyle, M. H., Sania, A., Pini, N., Babineau, V., Firestein, M. R., Fernández, C. R., Shuffrey, L. C., Barbosa, J. R., Rodriguez, C., Fifer, W. P., Alcántara, C., Monk, C., & Dumitriu, D. (2022). Postpartum sleep health in a multiethnic cohort of women during the COVID-19 pandemic in New York City. Sleep Health, 8(2), 175–182. https://doi.org/10.1016/j.sleh.2021.10.009
Callaghan, B., McCormack, C., Tottenham, N., & Monk, C. (2022). Evidence for cognitive plasticity during pregnancy via enhanced learning and memory. Memory (Hove, England), 1–18. Advance online publication. https://doi.org/10.1080/09658211.2021.2019280
Shuffrey, L. C., M. R. Firestein, M. H. Kyle, A. Fields, C. Alcántara, D. Amso, J. Austin, J. M. Bain, J. Barbosa, M. Bence, C. Bianco, C. R. Fernández, S. Goldman, C. Gyamfi-Bannerman, V. Hott, Y. Hu, M. Hussain, P. Factor-Litvak, M. Lucchini, A. Mandel, R. Marsh, D. McBrian, M. Mourad, R. Muhle, K. G. Noble, A. A. Penn, C. Rodriguez, A. Sania, W. G. Silver, K. C. O’Reilly, M. Stockwell, N. Tottenham, M. G. Welch, N. Zork, W. P. Fifer, C. Monk and D. Dumitriu (2022). Association of Birth During the COVID-19 Pandemic With Neurodevelopmental Status at 6 Months in Infants With and Without In Utero Exposure to Maternal SARS-CoV-2 Infection. JAMA Pediatrics: e215563-e215563.
Raiff, E. M., D'Antonio, K. M., Mai, C., & Monk, C. (2022). Mental Health in Obstetric Patients and Providers During the COVID-19 Pandemic. Clinical Obstetrics and Gynecology, 65(1), 203–215. https://doi.org/10.1097/GRF.0000000000000668
Miller, E. S., Saade, G. R., Simhan, H. N., Monk, C., Haas, D. M., Silver, R. M., Mercer, B. M., Parry, S., Wing, D. A., Reddy, U. M., & Grobman, W. A. (2022). Trajectories of antenatal depression and adverse pregnancy outcomes. American Journal of Obstetrics and Gynecology, 226(1), 108.e1–108.e9. https://doi.org/10.1016/j.ajog.2021.07.007
Takács, L., Babineau, V., Monk, C. (2022). Stress in pregnancy: Impacts on mother and child. In: Hutner, L. A., Catapano, L. A., Nagle-Yang, S. M., Williams, K. E., & Osborne, L. M. (Eds.). Textbook of Women's Reproductive Mental Health. American Psychiatric Pub. ISBN 978-1-61537-306-2.
2021
Rausser, S., Trumpff, C., McGill, M. A., Junker, A., Wang, W., Ho, S. H., Mitchell, A., Karan, K. R., Monk, C., Segerstrom, S. C., Reed, R. G., & Picard, M. (2021). Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures. eLife, 10, e70899. https://doi.org/10.7554/eLife.70899
Logue, T. C., Wen, T., Monk, C., Guglielminotti, J., Huang, Y., Wright, J. D., D'Alton, M. E., & Friedman, A. M. (2021). Trends in and complications associated with mental health condition diagnoses during delivery hospitalizations. American Journal of Obstetrics and Gynecology, S0002-9378(21)01049-8. Advance online publication. https://doi-org.ezproxy.cul.columbia.edu/10.1016/j.ajog.2021.09.021
Takács, L., Putnam, S. P., Bartoš, F., Čepický, P., & Monk, C. (2021). Parity moderates the effect of delivery mode on maternal ratings of infant temperament. PloS one, 16(8), e0255367. https://doi.org/10.1371/journal.pone.0255367
Berger, P. K., Monk, C., Bansal, R., Sawardekar, S., Goran, M. I., & Peterson, B. S. (2021). Association of Prenatal Sugar Consumption with Newborn Brain Tissue Organization. Nutrients, 13(7), 2435. https://doi-org.ezproxy.cul.columbia.edu/10.3390/nu13072435
Scorza, P., Merz, E. C., Spann, M., Steinberg, E., Feng, T., Lee, S., Werner, E., Peterson, B. S., & Monk, C. (2021). Pregnancy-specific stress and sensitive caregiving during the transition to motherhood in adolescents. BMC Pregnancy and Childbirth, 21(1), 458. https://doi-org.ezproxy.cul.columbia.edu/10.1186/s12884-021-03903-5
Wang, Y., Hinds, W., Duarte, C. S., Lee, S., Monk, C., Wall, M., Canino, G., Milani, A., Jackowski, A., Mamin, M. G., Foerster, B. U., Gingrich, J., Weissman, M. M., Peterson, B. S., Semanek, D., Perez, E. A., Labat, E., Torres, I. B., Da Silva, I., Parente, C., … Posner, J. (2021). Intra-session test-retest reliability of functional connectivity in infants. NeuroImage, 239, 118284. Advance online publication. https://doi-org.ezproxy.cul.columbia.edu/10.1016/j.neuroimage.2021.118284
Berry, O. O., Babineau, V., Lee, S., Feng, T., Scorza, P., Werner, E. A., & Monk, C. (2021). Perinatal depression prevention through the mother-infant dyad: The role of maternal childhood maltreatment. Journal of Affective Disorders, 290, 188–196. Advance online publication. https://doi-org.ezproxy.cul.columbia.edu/10.1016/j.jad.2021.04.068
Takács, L., Štipl, J., Gartstein, M., Putnam, S. P., & Monk, C. (2021). Social support buffers the effects of maternal prenatal stress on infants' unpredictability. Early Human Development, 157, 105352. doi:https://doi.org/10.1016/j.earlhumdev.2021.105352
Foss, S., Gustafsson, H. C., Berry, O. O., Hipwell, A. E., Werner, E. A., Peterson, B. S., & Monk, C. (2021). Associations between childhood maltreatment, poor sleep, and prenatal distress in pregnant adolescents. Development and Psychopathology, 1–10. Advance online publication. https://doi-org.ezproxy.cul.columbia.edu/10.1017/S0954579420002163
Trumpff, C., Sturm, G., Picard, M., Foss, S., Lee, S., Feng, T., Cardenas, A., McCormack, C., Champagne, F. A., & Monk, C. (2021). Added sugar intake during pregnancy: Fetal behavior, birth outcomes, and placental DNA methylation. Developmental Psychobiology, 10.1002/dev.22088. Advance online publication. https://doi-org.ezproxy.cul.columbia.edu/10.1002/dev.22088
Pingeton, B. C., Goodman, S. H., & Monk, C. (2021). Prenatal origins of temperament: Fetal cardiac development & infant surgency, negative affectivity, and regulation/orienting. Infant Behavior and Development, 65, 101643. https://doi.org/10.1016/j.infbeh.2021.101643
Berger, P., Monk, C., Bansal, R., Sawardekar, S., Plows, J., Alderete, T., ... & Peterson, B. (2021). Association of Prenatal Zinc Consumption With Newborn Brain Tissue Organization and Resting Cerebral Blood Flow. Current Developments in Nutrition, 5(Supplement_2), 718-718. https://doi.org/10.1093/cdn/nzab046_015
2020
Berry, O. O., & Monk, C. (2020). Intimate partner violence and psychological interventions in low-income and middle-income countries. The lancet. Psychiatry, 7(2), 114–116. https://doi.org/10.1016/S2215-0366(19)30530-9
Scorza, P., Monk, C., Lee, S., Feng, T., Berry, O. O., & Werner, E. (2020). Preventing maternal mental health disorders in the context of poverty: pilot efficacy of a dyadic intervention. American Journal of Obstetrics & Gynecology MFM, 2(4), 100230. https://doi-org.ezproxy.cul.columbia.edu/10.1016/j.ajogmf.2020.100230
Merz, E. C., Monk, C., Bansal, R., Sawardekar, S., Lee, S., Feng, T., Spann, M., Foss, S., McDonough, L., Werner, E., & Peterson, B. S. (2020). Neonatal brain metabolite concentrations: Associations with age, sex, and developmental outcomes. PloS one, 15(12), e0243255. https://doi-org.ezproxy.cul.columbia.edu/10.1371/journal.pone.0243255
Spann MN, Scheinost D, Feng T, Barbato K, Lee S, Monk C, Peterson BS. Association of Maternal Prepregnancy Body Mass Index With Fetal Growth and Neonatal Thalamic Brain Connectivity Among Adolescent and Young Women. JAMA Netw Open. 2020 Nov 2;3(11):e2024661. doi: 10.1001/jamanetworkopen.2020.24661. PMID: 33141162.
McCormack, C., & Monk, C. (2020). Considering Prenatal Alcohol Exposure in a Developmental Origins of Health and Disease Framework. American Journal of Psychiatry, 177(11), 1025-1028. doi:10.1176/appi.ajp.2020.20091376
Takács, L., Putnam, S. P., Monk, C., Dahlen, H. G., Thornton, C., Bartoš, F., Topalidou, A., & Peters, L. L. (2020). Associations Between Mode of Birth and Neuropsychological Development in Children Aged 4 Years: Results from a Birth Cohort Study. Child Psychiatry and Human Development, 10.1007/s10578-020-01084-4. Advance online publication. https://doi-org.ezproxy.cul.columbia.edu/10.1007/s10578-020-01084-4
Reuveni, I., Lauria, M., Monk, C., Werner, E. (2020). The impact of childhood trauma on psychological interventions for depression during pregnancy and postpartum: a systematic review. Arch Womens Ment Health. https://doi-org.ezproxy.cul.columbia.edu/10.1007/s00737-020-01066-4
McCormack, C., Lauriola, V., Feng, T., Lee, S., Spann, M., Mitchell, A., Champagne, F., & Monk, C. (2020). Maternal childhood adversity and inflammation during pregnancy: Interactions with diet quality and depressive symptoms. Brain, Behavior, and Immunity, S0889-1591(20)31116-8. Advance online publication. https://doi-org.ezproxy.cul.columbia.edu/10.1016/j.bbi.2020.09.023
Werner, E. A., Aloisio, C. E., Butler, A. D., D'Antonio, K. M., Kenny, J. M., Mitchell, A., Ona, S., & Monk, C. (2020). Addressing mental health in patients and providers during the COVID-19 pandemic. Seminars in Perinatology, 151279. Advance online publication. https://doi-org.ezproxy.cul.columbia.edu/10.1016/j.semperi.2020.151279
Scorza, P., Duarte, C. S., Lee, S., Wu, H., Posner, J. E., Baccarelli, A., & Monk, C. (2020). Epigenetic Intergenerational Transmission: Mothers' Adverse Childhood Experiences and DNA Methylation. Journal of the American Academy of Child and Adolescent Psychiatry, 59(7), 900–901. https://doi-org.ezproxy.cul.columbia.edu/10.1016/j.jaac.2020.03.008
Do, C., Dumont, E., Salas, M., Castano, A., Mujahed, H., Maldonado, L., Singh, A., DaSilva-Arnold, S. C., Bhagat, G., Lehman, S., Christiano, A. M., Madhavan, S., Nagy, P. L., Green, P., Feinman, R., Trimble, C., Illsley, N. P., Marder, K., Honig, L., Monk, C., … Tycko, B. (2020). Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs. Genome Biology, 21(1), 153. https://doi-org.ezproxy.cul.columbia.edu/10.1186/s13059-020-02059-3
Fernández, C. R., Chen, L., Cheng, E. R., Charles, N., Meyer, D., Monk, C., & Woo Baidal, J. (2020). Food Insecurity and Sugar-Sweetened Beverage Consumption Among WIC-Enrolled Families in the First 1,000 Days. Journal of Nutrition Education and Behavior, 52(8), 796–800. https://doi-org.ezproxy.cul.columbia.edu/10.1016/j.jneb.2020.03.006
Aziz, A., Zork, N., Aubey, J.J., Baptiste, C.D., D'Alton, M.E., Emeruwa, U.N., Fuchs, K.M., Goffman, D., Gyamfi-Bannerman, C., Haythe, J.H., LaSala, A.P., Madden, N., Miller, E.C., Miller, R.S., Monk, C., Moroz, L., Ona, S., Ring, L.E., Sheen, J.J., Spiegel, E.S., Simpson, L.L., Yates, H.S., Friedman, A.M. (2020). Telehealth for High-Risk Pregnancies in the Setting of the COVID-19 Pandemic. American Journal of Perinatology. https://dx.doi.org/10.1055/s-0040-1712121
Scheinost, D., Spann, M.N., McDonough, L., Peterson, B.S., Monk, C. (2020). Associations between different dimensions of prenatal distress, neonatal hippocampal connectivity, and infant memory. Neuropsychopharmacology. https://doi.org/10.1038/s41386-020-0677-0
Robakis, T. K., Lee, S., Werner, E., Liu, G., Miller, M., Wylie, D., Champagne, F. A., Salas, M., Do, C., Tycko, B., & Monk, C. (2020). DNA methylation patterns in T lymphocytes are generally stable in human pregnancies but CD3 methylation is associated with perinatal psychiatric symptoms. Brain, Behavior, & Immunity - health, 3, 100044. https://doi.org/10.1016/j.bbih.2020.100044
Padula, A.M., Monk, C., Brennan, P.L., Borders, A., Barrett, E.S., McEvoy, C.T., Foss, S., Desai, P., Alshawabkeh, A., Wurth, R., Salafia, C., Fichorova, R., Varshavsky, J., Kress, A., Woodruff, T.J., Morell-Frosch, R. (2020). A review of maternal prenatal exposures to environmental chemicals and psychosocial stressors - implications for research on perinatal outcomes in the ECHO Program. Journal of Perinatology, 40(1), 10-24. https://doi.org/10.1038/s41372-019-0510-y
Duarte, C.S., Monk, C., Weissman, M.M., Posner, J. (2020). Intergenerational psychiatry: a new look at a powerful perspective. World Psychiatry,19(2), 175-176. https://doi.org/10.1002/wps.20733open_in_new
O’Sullivan, A., Monk, C. (2020) Maternal and environmental influences on perinatal and infant development. Future of Children, 30 (2), pp. 11-34.
Maguire, J., McCormack, C., Mitchell, A., & Monk, C. (2020). Neurobiology of maternal mental illness. Handbook of clinical neurology, 171, 97–116. https://doi-org.ezproxy.cul.columbia.edu/10.1016/B978-0-444-64239-4.00005-9
Hermann, A., Deligiannidis, K. M., Bergink, V., Monk, C., Fitelson, E. M., Robakis, T. K., & Birndorf, C. (2020). Response to SARS-Covid-19-related visitor restrictions on labor and delivery wards in New York City. Archives of women's mental health, 23(6), 793–794. https://doi.org/10.1007/s00737-020-01030-2
2019
Monk, C., Lugo-Candelas, C., Trumpff, C. Prenatal Developmental Origins of Future Psychopathology: Mechanisms and Pathways. Annu Rev Clin Psychol. 2019 May 7;15:317-344. doi: 10.1146/annurev-clinpsy-050718-095539. Epub 2019 Feb 22. PMID: 30795695; PMCID: PMC7027196.
Walsh, K., McCormack, C.A., Webster, R., Pinto, A., Lee, S., Feng, T.H., Krakovsky, S., O’Grady, S.M., Tycko, B., Champagne, F.A., Werner, E.A., Liu, G., Monk, C. (2019). Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.1905890116 [Download Supplementary Materials]
Berger-Jenkins, E., Monk, C., D'Onfro, K., Sultana, M., Brandt, L., Ankam, J., ... & Meyer, D. (2019). Screening for Both Child Behavior and Social Determinants of Health in Pediatric Primary Care. Journal of Developmental & Behavioral Pediatrics, 40(6), 415-424. doi: 10.1097/DBP.0000000000000676.
Monk, C., Webster, R. S., McNeil, R. B., Parker, C. B., Catov, J. M., Greenland, P., ... & Chung, J. H. (2019). Associations of perceived prenatal stress and adverse pregnancy outcomes with perceived stress years after delivery. Archives of Women's Mental Health, 1-9. https://doi.org/10.1007/s00737-019-00970-8
Spicer, J., Giesbrecht, G. F., Aboelela, S., Lee, S., Liu, G., Monk, C. (2019). Ambulatory Blood Pressure Trajectory and Perceived Stress in relation to Birth Outcomes in Healthy Pregnant Adolescents. Psychosomatic Medicine, 81(5), 464-476. doi: 10.1097/PSY.0000000000000698. PMID: 31090671; PMCID: PMC6715293.
Grieve, P.G., Fifer, W.P., Cousy, N.P., Monk, C., Stark, R.I, Gingrich, J.A., Myers, M.M. (2019). Neonatal infant EEG bursts are altered by prenatal maternal depression and SSRI use. Clinical Neurophysiology, 130(11), 2019-2025. https://doi.org/10.1016/j.clinph.2019.08.021
Mangla, K., Hoffman, M. C., Trumpff, C., O’Grady, S. M., Monk, C. (2019). Maternal Self-Harm Deaths: An Unrecognized and Preventable Outcome. American Journal of Obstetrics and Gynecology. 1-9. 5 March 2019. https://doi.org/10.1016/j.ajog.2019.02.056
McIntyre, K. M., Mogle, J. A., Scodes, J. M., Pavlicova, M., Shapiro P. A., Gorenstein E. A., Tager F. A., Monk C., Almeida D. M., Sloan R. P. (2019). Anger-reduction treatment reduces negative affect reactivity to daily stressors. Journal of Consulting and Clinical Psychology, 87, 141-150. https://psycnet.apa.org/doi/10.1037/ccp0000359
Miller ES, Saade GR, Simhan HN, et al. Trajectories of antenatal depression and adverse pregnancy outcomes. Am J Obstet Gynecol 2022;226:108.e1-9. https://doi.org/10.1016/j.ajog.2021.07.007
Hipwell, A. E., Kahn, L. G., Factor-Litvak, P., Porucznik, C. A., Siegel, E. L., Fichorova, R. N., Hamman, R. F., Klein-Fedyshin, M., Harley, K. G., & program collaborators for Environmental influences on Child Health Outcomes (2019). Exposure to non-persistent chemicals in consumer products and fecundability: a systematic review. Human Reproduction Update, 25(1), 51–71. https://doi.org/10.1093/humupd/dmy032
Lin, B., Kaliush, P. R., Conradt, E., Terrell, S., Neff, D., Allen, A. K., Smid, M. C., Monk, C., & Crowell, S. E. (2019). Intergenerational transmission of emotion dysregulation: Part I. Psychopathology, self-injury, and parasympathetic responsivity among pregnant women. Development and psychopathology, 31(3), 817–831. https://doi.org/10.1017/S0954579419000336
Ostlund, B. D., Vlisides-Henry, R. D., Crowell, S. E., Raby, K. L., Terrell, S., Brown, M. A., Tinajero, R., Shakiba, N., Monk, C., Shakib, J. H., Buchi, K. F., & Conradt, E. (2019). Intergenerational transmission of emotion dysregulation: Part II. Developmental origins of newborn neurobehavior. Development and psychopathology, 31(3), 833–846. https://doi.org/10.1017/S0954579419000440
2018
Osborne, L. M., Yenokyan, G., Fei, K., Kraus, T., Moran, T., Monk, C., & Sperling, R. (2018). Innate immune activation and depressive and anxious symptoms across the peripartum: An exploratory study. Psychoneuroendocrinology, 99, 80-86. https://doi.org/10.1016/j.psyneuen.2018.08.038
Scorza, P., Duarte, C.S., Hipwell, A.E., Posner, J., Ortin, A., Canino, G. & Monk, C. (2018). Research Review: Intergenerational transmission of disadvantage: epigenetics and parents’ childhoods as the first exposure. Journal of Child Psychology and Psychiatry, 2019 Feb;60(2):119-132. doi: 10.1111/jcpp.12877. Epub 2018 Feb 23. PMID: 29473646; PMCID: PMC6107434.
Conradt, E., Adkins, D., Crowell, S. E., Monk, C., & Kobor, M. (2018). An epigenetic pathway approach to investigating associations between prenatal exposure to maternal mood disorder and newborn neurobehavior. Development and Psychopathology, 30, 881-890. doi: 10.1017/S0954579418000688. PMID: 30068429; PMCID: PMC6074043.
Gustafsson, H. C., Goodman, S. H., Feng, T., Choi, J., Lee, S., Newport, D. J., Knight, B., Pingeton, B., Stowe, Z., & Monk, C. (2018). Major depressive disorder during pregnancy: Psychiatric medications have minimal effects on the fetus and infant yet development is compromised. Development and Psychopathology, 30, 733-785. doi:10.1017/S0954579418000639
Desai, P., Haber, H., Bulafka, J., Russell, A., Clifton, R., Zachary, J., Lee, S., Feng, T., Wapner, R., Monk, C., & Chung, W.K. (2018). Impacts of Variants of Uncertain Significance on Parental Perceptions of Children After Prenatal Chromosome Microarry Testing. Prenatal Diagnosis, 38(10), 740-747. https://doi.org/10.1002/pd.5323
Laurent, H., Goodman, S., Stowe, Z., Halperin, M., Khan, F., Wright, D., Nelson, B., Newport, D. J., Ritchie, J., Monk, C. & Knight, B. (2018). Course of ante- and postnatal depressive symptoms related to mothers’ HPA axis regulation. Journal of Abnormal Psychology, 127(4), 404-416. https://psycnet.apa.org/doi/10.1037/abn0000348
Lugo-Candelas, C., Cha, J., Hong, S., Bastidas, V., Weissman, M., Fifer, W., Myers, M., Talati, A., Bansal, R., Peterson, B., Monk, C., Gingrich, J., & Posner, J. (2018). Associations Between Brain Structure and Connectivity in Infants and Exposure to Selective Serotonin Reuptake Inhibitors During Pregnancy. JAMA Pediatrics, 172(6), 525–533. doi:10.1001/jamapediatrics.2017.5227
Spann, M. N., Monk, C., Scheinost, D., & Peterson, B. S. (2018). Maternal immune activation during the third trimester is associated with neonatal functional connectivity of the salience network and fetal to toddler behavior. Journal of Neuroscience, 38(11), 2877-2886. https://doi.org/10.1523/JNEUROSCI.2272-17.2018
Gustafsson, H.C., Grieve, P.G., Werner, E.A., Desai, P., & Monk, C. (2018). Newborn electroencephalographic correlates of maternal prenatal depressive symptoms. Journal of Developmental Origins of Health and Disease, 9(4), 381-385. https://doi.org/10.1017/S2040174418000089
Lugo-Candelas, C., Monk, C., Duarte, C. S., Lee, S., & Posner, J. (2018). Shared genetic factors, fetal programming, and the transmission of depression. The lancet. Psychiatry, 5(10), 771–773. https://doi.org/10.1016/S2215-0366(18)30356-0
Paneth, N., & Monk, C. (2018). The importance of cohort research starting early in life to understanding child health. Current opinion in pediatrics, 30(2), 292–296. https://doi.org/10.1097/MOP.0000000000000596
2017
Green, C., Babineau, V., Jolicoeur-Martineau, A., Bouvette-Turcot, A., Minde, K., Sassi, R., . . . Wazana, A. (2017). Prenatal maternal depression and child serotonin transporter linked polymorphic region (5-HTTLPR) and dopamine receptor D4 (DRD4) genotype predict negative emotionality from 3 to 36 months. Development and Psychopathology, 29(3), 901-917. doi:10.1017/S0954579416000560
Singh, A., Trumpff, C., Genkinger, J., Davis, A., Spann, M., Werner, E., Monk, C. (2017). Micronutrient Dietary intake in Latina Pregnant Adolescents and Its Association with Level of Depression, Stress, and Social Support. Nutrients, 9(11), 1212. https://doi.org/10.3390/nu9111212
Merz EC, McDonough L, Huang YL, Foss S, Werner E, Monk C. (2017). The mobile conjugate reinforcement paradigm in a lab setting. Developmental Psychobiology, 59(5), 668–672. https://doi.org/10.1002/dev.21520
Ecklund-Flores, L., Myers, M.M., Monk, C., Perez, A., Odendaal, H.J., Fifer, W.P. (2017). Maternal depression during pregnancy is associated with increased birth weight in term infants. Developmental Psychobiology, 59, 314-323. https://doi.org/10.1002/dev.21496
Gustafsson, H., Doyle, C., Gilchrist, M., Werner, E., Monk, C. (2017). Maternal abuse history and reduced fetal heart rate variability: Abuse-related sleep disturbance is a mediator. Development and Psychopathology, 29(3), 1023-1034. doi:10.1017/S0954579416000997
Helpman, L., Zhu, X., Suarez-Jimenez, B., Lazarov, A., Monk, C., Neria, Y. (2017). Sex Differences in Trauma-Related Psychopathology: a Critical Review of Neuroimaging Literature (2014-2017). Current Psychiatry Reports, 19(12), 104. https://doi.org/10.1007/s11920-017-0854-y
Weiss, M., Benavides, M. O., Fitelson, E., & Monk, C. (2017). The Domestic Violence Initiative: A Private-Public Partnership Providing Psychiatric Care in a Nontraditional Setting. Psychiatric services (Washington, D.C.), 68(2), 212. https://doi.org/10.1176/appi.ps.68204
2016
O'Connor, T. G., Monk, C., & Burke, A. S. (2016). Maternal Affective Illness in the Perinatal Period and Child Development: Findings on Developmental Timing, Mechanisms, and Intervention. Current psychiatry reports, 18(3), 24. https://doi.org/10.1007/s11920-016-0660-y
Walsh, K., Basu, A., Werner E., Lee, S., Feng, T., Osborne, L.M., Rainford, A., Gilchrist, M., Monk, C. (2016). Associations Among Child Abuse, Depression, and Interleukin-6 in Pregnant Adolescents: Paradoxical Findings. Psychosomatic Medicine, epub ahead of print.
Do, C., Lang, C.F., Lin, J., Krupska, I., Gaba, A., Darbary, H., Petukhova, L., Vonsatte, J.P., Gallagher, M.P., Goland, R.S., Clynes, R.A., Dwork, A., Kral, J.G., Monk, C., Christiano, A.M., Tycko, B. (2016). Mechanisms and disease associations of haplotype dependent allele specific DNA methylation. American Journal of Human Genetics, 98(5), 934-955.
Monk, C., Feng, T., Lee, S., Krupska, I., Champagne, F.A., Tycko, B. (2016). Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior. American Journal of Psychiatry, 173(7), 705-713.
Monk, C., Georgieff, M.K., Xu, D., Hao, X., Bansal, R., Gustafsson, H., Spicer, J., Peterson, B.S. (2016). Maternal Prenatal Iron Status and Tissue Organization in the Neonatal Brain. Pediatric Research 79(3), 482-488.
Werner, E.A., Gustafsson, H.C., Lee, S., Feng, T., Jiang, N., Desai, P., Monk, C. (2016). PREPP: postpartum depression prevention through the mother-infant dyad. Archives of Women’s Mental Health, 19(2), 229-242.
Posner, J., Cha, J., Roy, A.K., Peterson, B.S., Bansal, R., Gustafsson, H.C., Raffanello, E., Gingrich, J., Monk, C. (2016). Alterations in amygdala-prefrontal circuits in infants exposed to prenatal maternal depression. Translational Psychiatry, 6, e935.
Monk, C. (2016). 2.3 Using Epigenetics to Understand How Distress During Pregnancy Impacts Fetal Behavioral Outcomes. Journal of the American Academy of Child & Adolescent Psychiatry, 10(55), S86-S87.
2015
Babineau, V., Green, C.G., Jolicoeur-Martineau, A., Bouvette-Turcot, A.-A., Minde, K., Sassi, R., St-André, M., Carrey, N., Atkinson, L., Kennedy, J.L., Lydon, J., Steiner, M., Gaudreau, H., Levitan, R., Meaney, M., Wazana, A. and (2015), Prenatal depression and 5-HTTLPR interact to predict dysregulation from 3 to 36 months – A differential susceptibility model. J Child Psychol Psychiatr, 56: 21-29. https://doi.org/10.1111/jcpp.12247
Chapman, A. & Monk, C. (2015). Domestic Violence Awareness. The American Journal of Psychiatry, 172(10), 944-945. https://doi.org/10.1176/appi.ajp.2015.15070853
Gustafsson, H.C., Kuzava, S.E., Werner, E., Monk, C. (2015). Maternal Dietary Fat Intake During Pregnancy Is Associated With Infant Temperament. Developmental Psychobiology 58(4), 528-535.
Flood, P., McKinley, P., Monk, C., Muntner, P., Colantonio, L. D., Goetzl, L., Hatch, M., & Sloan, R. P. (2015). Beat-to-beat heart rate and blood pressure variability and hypertensive disease in pregnancy. American journal of perinatology, 32(11), 1050–1058. https://doi.org/10.1055/s-0035-1548542
Doyle C., Werner, E., Feng, T., Lee, S., Altemus, M., Isler, J.R. Monk, C. (2015). Pregnancy distress gets under fetal skin: Maternal ambulatory assessment & sex differences in prenatal development. Developmental Psychobiology, 57(5), 607-625.
Spann, M.N., Smerling, J., Gustafsson, H., Foss, S., Altemus, M., Monk, C. (2015). Deficient maternal zinc intake—but not folate—is associated with lower fetal heart rate variability. Early Human Development, 91(3), 169-172.
Walsh, K., Basu, A., Monk, C. (2015). The Role of Sexual Abuse and Dysfunctional Attitudes in Perceived Stress and Negative Mood in Pregnant Adolescents: An Ecological Momentary Assessment Study. Journal of Pediatric Adolescent Gynecology, 28(5), 327-32.
Werner, E., Miller, M., Osborne, L. M., Kuzava, S., & Monk, C. (2015). Preventing postpartum depression: review and recommendations. Archives of Women’s Mental Health, 18(1), 41–60. https://doi.org/10.1007/s00737-014-0475-y
2014
O'Connor, T. G., Monk, C., & Fitelson, E. M. (2014). Practitioner review: maternal mood in pregnancy and child development--implications for child psychology and psychiatry. Journal of child psychology and psychiatry, and allied disciplines, 55(2), 99–111. https://doi.org/10.1111/jcpp.12153
Logsdon, M.C., Monk, C., & Hipwell, A. E. (2014). Chapter 28: Perinatal Experiences of Adolescent Mothers. The Oxford Handbook of Perinatal Psychology, pp. 574–601. https://doi.org/10.1093/oxfordhb/9780199778072.013.008
Monk, C., & Hane, A.A (2014). Chapter 5: Fetal and Infant Neurobehavioral Development. The Oxford Handbook of Perinatal Psychology, pp. 53-86. https://doi.org/10.1093/oxfordhb/9780199778072.013.20
Spicer, J., Gustafsson, H., Werner, E., Kuzava, S., Monk, C. (2014). ALLOSTATIC LOAD DURING PREGNANCY IS ASSOCIATED WITH GESTATIONAL AGE AT BIRTH. Psychosomatic Medicine A4-A4.
2013
Monk, C., Georgieff, M. K., & Osterholm, E. A. (2013). Research review: maternal prenatal distress and poor nutrition - mutually influencing risk factors affecting infant neurocognitive development. Journal of child psychology and psychiatry, and allied disciplines, 54(2), 115–130. https://doi.org/10.1111/jcpp.12000
Spicer, J., Werner, E., Zhao, Y., Chien, W.C., Lopez-Pintado, S., Feng, T., Altemus, M., Gyamfi, C., Monk, C. (2013). Ambulatory assessments of psychological and peripheral stress-markers predict birth outcomes in teen pregnancy. Journal of Psychosomatic Research, 75(4), 305-314.
Werner, E., Zhao, Y., Evans, L., Kinsella, M., Kurzius, L., Altincatal, A., McDonough, L., Monk, C. (2013). Higher Maternal Prenatal Cortisol and Younger Age Predict Greater Infant Reactivity to Novelty at 4 Months: An Observation-Based Study. Developmental Psychobiology, 55(7), 707-719.
Osborne, L. M., & Monk, C. (2013). Perinatal depression--the fourth inflammatory morbidity of pregnancy?: Theory and literature review. Psychoneuroendocrinology, 38(10), 1929–1952. https://doi.org/10.1016/j.psyneuen.2013.03.019
2012
Jensen Peña, C., Monk, C., Champagne, F.A. (2012). Epigenetic Effects of Prenatal Stress on 11b-Hydroxosteroid Dehydrogenase-2 in the Placenta and Fetal Brain. PLOS ONE 7(6), 1-9.
Monk, C., Newport, D.J., Korotkin, L.H., Long, Q., Knight, B., Stowe, Z.N. (2012). Uterine Blood Flow in a Psychiatric Population: Impact of Maternal Anxiety, Depression, and Psychotropic Medication. Biological Psychology, 72(6), 483-490.
Channing, A., Rosenberg, K., Monk, C., Kleinman, C.S., Glickstein, J.S., Levasseur, S.M., Simpson, L.L., Williams, I.A. (2012). Maternal anxiety associated with fetal echocardiography. Open Journal of Pediatrics, 2, 143-149.
Monk, C., Spicer, J., & Champagne, F. A. (2012). Linking prenatal maternal adversity to developmental outcomes in infants: the role of epigenetic pathways. Development and psychopathology, 24(4), 1361–1376. https://doi.org/10.1017/S0954579412000764
2011
Monk, C., Fitelson, E. M., & Werner, E. (2011). Mood disorders and their pharmacological treatment during pregnancy: is the future child affected?. Pediatric research, 69(5 Pt 2), 3R–10R. https://doi.org/10.1203/PDR.0b013e3182131a2e
Monk, C., Fifer, W.P., Myers, M.M., Bagiella, E., Duong, J.K., Chen, I.S., Leotti, L. and Altincatal, A. (2011). Effects of maternal breathing rate, psychiatric status, and cortisol on fetal heart rate. Dev. Psychobiol., 53: 221-233. https://doi.org/10.1002/dev.20513
Rohan, A. J., Monk, C., Marder, K., & Reame, N. (2011). Prenatal toxicology screening for substance abuse in research: codes and consequences. Substance abuse, 32(3), 159–164. https://doi.org/10.1080/08897077.2011.560526
2010
Bauer, S., Monk, C., Ansorge, M., Gyamfi, C., Myers, M. (2010). Impact of antenatal selective serotonin reuptake inhibitor exposure on pregnancy outcomes in mice. American Journal of Obstetric Gynecology, 203:375, e1-4.
Rosenberg, K.B., Monk, C., Glickstein, J.S., Levasseur, S.M., Simpson, L.L., Kleinman, C.S., Williams, I.A. (2010). Referral for fetal echocardiography is associated with increased maternal anxiety. Journal of Psychosomatic Obstetrics & Gynecology, 31(2), 60-69.
Sloan, R.P., Shapiro, P.A., Gorenstein, E.E., Tager, F.A., Monk, C.E., McKinley, P.S., Myers, M.M., Bagiella, E., Chen, I., Steinman, R., Bigger, J.T. (2010). Cardiac Autonomic Control and Treatment of Hostility: A Randomized Controlled Trial. Psychosomatic Medicine, 72(1), 1-8.
2009 and earlier
Kinsella, M. T., & Monk, C. (2009). Impact of maternal stress, depression and anxiety on fetal neurobehavioral development. Clinical obstetrics and gynecology, 52(3), 425–440. https://doi.org/10.1097/GRF.0b013e3181b52df1
Monk, C., Fifer, W., Myers, M.. Newport, D.J., Stowe, Zachary. (2009). Perinatal Endophenotype Related to Women's Antenatal Depression and SSRI Use. 20S-21S.
Bauer, S., Monk, C., Ansorge, M., Gyamfi, C., Myers, M. (2009) 707: Impact of antenatal selective serotonin reuptake inhibitor exposure on length of gestation and pregnancy loss in mice. Poster Session V Fetus Diabetes, Antepartum Fetal Assessment, Genetics, Hypertension, Medical-Surgical Complication. 201(6), S256.
Bauer, S., Monk, C., Ansorge, M., Gyamfi, C., Myers, M. (2009) 99: Pregnancy outcomes in mice following antenatal selective serotonin reuptake inhibitor exposure. Poster Session I Clinical Obstetrics, Neonatology, Physiology-Endocrinology. 201(6), S256.
Bergner, S., Monk, C., & Werner, E. A. (2008). Dyadic Intervention during Pregnancy? Treating Pregnant Women and Possibly Reaching the Future Baby. Infant mental health journal, 29(5), 399–419. https://doi.org/10.1002/imhj.20190
Evans, L.M., Myers, M.M., Monk, C. (2008). Pregnant women’s cortisol is elevated with anxiety and depression – but only when comorbid. Archives of Women’s Mental Health, 11(3), 239-248.
Monk, C., Leight, K.L., Fang, Y. (2008). The relationship between women’s attachment style and perinatal mood disturbance: implications for screening and treatment. Archives of Women’s Mental Health, 11(2), 117-129.
Kaplan, L.A., Evans, L., Monk, C. (2008). Effects of mothers’ prenatal psychiatric status and postnatal caregiving on infant biobehavioral regulation: Can prenatal programming be modified? Early Human Development, 84(4), 249-256.
Gorenstein, E. E., Tager, F. A., Shapiro, P. A., Monk, C., & Sloan, R. P. (2007). Cognitive-Behavior Therapy for Reduction of Persistent Anger. Cognitive and Behavioral Practice, 14(2), 168–184. https://doi.org/10.1016/j.cbpra.2006.07.004
Werner, E.A., Myers, M.M., Fifer, W.P., Cheng, B., Fang, Y., Allen, R., Monk, C. (2007). Prenatal Predictors of Infant Temperament. Developmental Psychobiology, 49(5), 474-484.
Werner, E., & Monk, C. (2005). Review of forms of intersubjectivity in infant research and adult attachment. Psychotherapy (Chicago, Ill.), 43(3), 362–363. https://doi.org/10.1037/0033-3204.43.3.362
Monk, C., Sloan, R.P., Myers, M.M., Ellman, L., Werner, E., Jeon, J., Tager, F., Fifer, W.P. (2004). Fetal Heart Rate Reactivity Differs by Women’s Psychiatric Status: An Early Marker for Developmental Risk? Journal of American Academic Child Adolescent Psychiatry, 43(3), 283-290.
Fifer, W., Monk, C. Grose-Fifer, J. (2004). Chapter 18: Prenatal Development and Risk. Blackwell handbook of infant development. Oxford, UK: Malden, Mass., USA. doi:10.1002/9780470996348.ch18
Monk, C., Myers, M.M., Sloan, R.P., Ellman, L.M., and Fifer, W.P. (2003). Effects of Women’s Stress-Elicited Physiological Activity and Chronic Anxiety on Fetal Heart Rate. Developmental and Behavioral Pediatrics, 24(1), 32-38.
Monk, C., Fifer, W.P., Sloan, R.P., Myers, M.M., Bagiella, E., Ellman, L., Hurtado, A. (2001). Physiologic responses to cognitive challenge during pregnancy: effects of task and repeat testing. International Journal of Psychophysiology, 40(2), 149-159.
Monk, C. (2001). Stress and mood disorders during pregnancy: Implications for child development. Psychiatric Quarterly. doi:10.1023/A:1010393316106
Monk, C., Kovelenko, P., Ellman, L.M., Sloan, R.P., Bagiella, E., Gorman, J.M., and Pine, D.S. (2001). Enhanced stress reactivity in paediatric anxiety disorders: implications for future cardiovascular health. International Journal of Neuropsychopharmacology, 4(2), 199-206.
Monk, C., Fifer, W.P., Myers, M.M., Sloan, R.P., Trien, L., Hurtado, A. (1999). Maternal Stress Responses and Anxiety during Pregnancy: Effects on Fetal Heart Rate. Developmental Psychobiology, 36(1), 67-77.
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